Search results for " 112"

showing 10 items of 87 documents

Epigenetic Regulation of Cardiac Differentiation of Embryonic Stem Cells and Tissues.

2016

International audience; Specific gene transcription is a key biological process that underlies cell fate decision during embryonic development. The biological process is mediated by transcription factors which bind genomic regulatory regions including enhancers and promoters of cardiac constitutive genes. DNA is wrapped around histones that are subjected to chemical modifications. Modifications of histones further lead to repressed, activated or poised gene transcription, thus bringing another level of fine tuning regulation of gene transcription. Embryonic Stem cells (ES cells) recapitulate within embryoid bodies (i.e., cell aggregates) or in 2D culture the early steps of cardiac developme…

0301 basic medicineCellular differentiationGeneral Chemical Engineering[SDV]Life Sciences [q-bio]Human Embryonic Stem Cellscardiac developmentcardiac differentiationEmbryoid bodychromatin immunoprecipitationBiologyGeneral Biochemistry Genetics and Molecular BiologyEpigenesis GeneticHistones03 medical and health sciencesMiceIssue 112AnimalsHumansEpigeneticsEnhancerTranscription factorGeneticsGeneral Immunology and MicrobiologyGeneral NeurosciencePromoterCell DifferentiationHeartgene transcription regulationEmbryonic stem cellES cellsCell biology[SDV] Life Sciences [q-bio]030104 developmental biologyEpigeneticsChromatin immunoprecipitationDevelopmental Biology
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A phase I study of nintedanib combined with cisplatin/gemcitabine as first-line therapy for advanced squamous non-small cell lung cancer (LUME-Lung 3)

2018

Abstract Background There are limited treatment options for squamous non-small cell lung cancer (sqNSCLC) and prognosis remains poor. The safety and pharmacokinetics (PK) of nintedanib, a triple angiokinase inhibitor, plus cisplatin/gemcitabine as first-line treatment for advanced sqNSCLC patients, were evaluated. Materials and methods A phase I, dose-escalation study administering drugs in a 21-day cycle: cisplatin (75 mg/m2, Day 1), gemcitabine (1250 mg/m2, Days 1 and 8) and nintedanib (Days 2–7, 9–21) were given for 4–6 cycles, followed by monotherapy until disease progression or adverse events (AEs). Two nintedanib doses were tested, 150 mg twice daily (bid) and 200 mg bid, to determine…

0301 basic medicineOncologyMaleCancer ResearchPHARMACOKINETICSIndolesLung NeoplasmsPACLITAXELDeoxycytidineANGIOGENESISSquamouschemistry.chemical_compound0302 clinical medicineNon-small cell lung cancerCarcinoma Non-Small-Cell LungAntineoplastic Combined Chemotherapy ProtocolsBIBF 1120Aged 80 and overMiddle AgedPrognosisTreatment OutcomeOncologyPaclitaxelLABEL DOSE-ESCALATION030220 oncology & carcinogenesisNintedanibFemaleCLINICAL-PRACTICE GUIDELINESmedicine.drugPulmonary and Respiratory Medicinemedicine.medical_specialtyBevacizumabMaximum Tolerated DoseNintedanibBEVACIZUMABCONTROLLED-TRIALDisease-Free Survival03 medical and health sciencesPharmacokineticsInternal medicinemedicineHumansAdverse effectAgedNeoplasm StagingTRIPLE ANGIOKINASE INHIBITORCisplatinCARBOPLATINbusiness.industryGemcitabineCarboplatinGemcitabine030104 developmental biologychemistryCisplatinbusinessLung Cancer
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Martínez Nadal, A.: Big data, cloud computing y otros retos jurídicos planteados por las tecnologías emergentes, Thomson Reuters Aranzadi, 2019.

2021

:CIENCIAS JURÍDICAS [UNESCO]David 1118 1123cloud computing y otros retos jurídicos planteados por las tecnologías emergentesUNESCO::CIENCIAS JURÍDICAS2070-8157 22082 Revista Boliviana de Derecho 584568 2021 32 8055253 Martínez NadalThomson Reuters AranzadiBig data [A.]A.: Big data2019. López Jiménez
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Martínez Otero, J. Mª.: El ejercicio de la potestad sancionadora de la Administración en el ámbito audiovisual, Tirant lo Blanch, Valencia, 2021

2021

:CIENCIAS JURÍDICAS [UNESCO]UNESCO::CIENCIAS JURÍDICASEl ejercicio de la potestad sancionadora de la Administración en el ámbito audiovisual [J. Mª.]2021 Andrés SegoviaValenciaBelén 1124 1131Tirant lo BlanchJ. Mª.: El ejercicio de la potestad sancionadora de la Administración en el ámbito audiovisual2070-8157 22082 Revista Boliviana de Derecho 584568 2021 32 8055254 Martínez Otero
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Dilucidarium Augustini Niphi ... metaphysicarum disputationum in Aristotelis decem & quatuor libros metaphysicorum ex Arist. et Averrois ... ab aucto…

1559

Sign.: A-Z8 Retrat xil. d'Aristòtil a port. i de l'autor al v ̆de la port. Text a dos col. - Capll. historiades i orn.

Averrois Crítica i interpretació Obres anteriors a 1800Aristòtil 384-322 aC Crítica i interpretació Obres anteriors al 1800Averrois 1126-1198 Crítica i interpretació Obres anteriors al 1800Aristòtil (384-322 aC.) Crítica i interpretació Obres anteriors a 1800Metafísica Obres anteriors a 1800DIG-BHMetafísica Obres anteriors al 1800
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Expositio super libros Physicorum, vna cum textu Aristotelis, necnon super commentum Averrois

1499

Sign.: a10, b-i8, k6, l-x8, xx8, y8, z8, [erra cursiva]8, [um]8, [rum]8, A-X8, Y10, [4]. - Data completa, 23 abril, 1499 L. gòt. - 2 mides. - 2 col. - 63-64 lín. - Inic. grav. - Min. p. inic. - Registre. - Apost. marg. - Llegendes de foli. - Filigr.: estel amb balança encerclada

Averrois 1126-1198 Crítica i interpretació Obres anteriors al 1800Averrois 1126-1198 Crítica i interpretació Obres anteriors al 1800 lemacAristòtil 384-322 aC. Física Crítica i interpretació Obres anteriors al 1800 lemacAristòtil 384-322 aC. Física Crítica i interpretació Obres anteriors al 1800
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The interpretation of Bach's gamba sonata BWV 1029 on the cello

2006

Masteroppgave i utøvende musikk 2006 - Høgskolen i Agder, Kristiansand The interpretation of Bach’s gamba sonata BWV 1029 on the cello deals with the interpretation of gamba sonatas on the cello from the modern perspective. It is written in the English language by Ana Marinkovic and it is 55 pages long. It is a master thesis from the Agder University College, the Conservatory of Music in Kristiansand Norway, the classical department. Key words in my thesis are: Baroque style, analysis, interpretation, gamba and cello. I am trying to explore the historical interpretation of Baroque music, through the sonata BWV1029 which was written in that period by Johan Sebastian Bach (1685- 1750). Accord…

Baroque styleMUR500MUK500VDP::Humaniora: 0::Musikkvitenskap: 110::Musikkteori: 112InterpretationCelloGambaAnalysisVDP::Humaniora: 0::Musikkvitenskap: 110::Annen musikkvitenskap: 119
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Ottonis Episcopi Frisingensis ... Chronicon ... ; Eiusdem de gestis Friderici I ... Libri duo. Radeuici Frising. Canonici ... de eiusdem Frid. gestis…

Sig. *8, a-ff6, [creu llatina]8, A-S6 Capitals grav Reclams

Frederic I emperador romanogermànic ca. 1123-1190 Obres anteriors al 1800
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Gozos a San Julian, segundo Obispo de Cuenca : Nació en la Ciudad de Burgos en el año 1128 y murió en la de Cuenca en el de 1208.

El full orlat Grav. xil. enmarcat del sant, flanquejat per gerros amb flors Text del goig a tres col. separades per filets

Julià sant 1128-1208 Goigs
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Altfløytas kvaliteter og utfordringer : med en analyse av Konrad Øhrns Suite for altfløyte og piano; sommerminner

2013

Masteroppgaver i klassisk musikk- Universitetet i Agder 2013 Denne oppgaven tar for seg altfløyta og dens utfordringer og kvaliteter. Oppgaven har en teoretisk del som tar for seg altfløytas historie og utvikling, tekniske aspekter, fysiske forutsetninger, embouchure, klang og intonasjon, samt artikulasjon. Dette blir brukt videre i neste del som tar for seg Konrad Øhrns suite for altfløyte og klaver, Sommerminner. Her foretas det en analyse av verket på et instrumentteknisk nivå, med utgangspunkt i det tidligere kapitlet som omtaler de utfordringer og kvaliteter altfløyta har. Oppgaven tar også for seg forskjellene mellom c-fløyta og altfløyta, og om Sommerminner egner seg best for c-fløyt…

MUK 500VDP::Humanities: 000::Musicology: 110::Music theory: 112
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